Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (2S)- (9Ci) is a high-purity, chiral bicyclic olefin derivative that serves as a critical advanced pharmaceutical intermediate and a versatile building block in asymmetric synthesis. Its unique strained structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with high precision. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandins, antiviral agents, and other bioactive molecules requiring the norbornene scaffold.
• Asymmetric Catalysis Ligand Precursor: Used to develop and manufacture novel chiral ligands and organocatalysts for enantioselective transformations.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with unique thermal and mechanical properties via ring-opening metathesis polymerization (ROMP).
• Agrochemical Synthesis: Employed as a building block for creating chiral pesticides and herbicides with enhanced efficacy and environmental profiles.
• Fine Chemical Research: Utilized in academic and industrial R&D for exploring new reaction pathways and constructing complex, strained-ring natural product analogs.
• Flavor & Fragrance Ingredient Synthesis: Acts as a starting material for synthesizing specific terpenoid and musk-related compounds.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (2S)- (9Ci)
CAS No.	274255-59-3
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(2S)-2-Methoxycarbonylbicyclo[2.2.1]hept-5-ene; (1S,4R)-Methyl 2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate (related isomer); Methyl (1S,4R)-1,4-dihydro-1,4-methanonaphthalene-5-carboxylate; (S)-Methyl 5-norbornene-2-carboxylate; endo-Methyl 5-norbornene-2-carboxylate; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, methyl ester, (1S,4R)-; Norbornene methyl ester derivative
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (2S)- is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available for each lot upon request. Our quality protocols are designed to support cGMP compliance for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.