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Ethyl 2,2-Difluoro-2-(2-Pyridyl)Acetate CAS NO 267876-28-8


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CAS No.:267876-28-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 2,2-Difluoro-2-(2-Pyridyl)Acetate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoroacetate moiety adjacent to the pyridine ring, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex intermediates.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
  • Ligand Precursor: Serves as a starting material for synthesizing novel nitrogen-containing ligands used in catalysis and material science.
  • Fluorine Chemistry Research: An important reagent for studying new fluorination reactions and developing methodologies for introducing difluoroacetate groups.
  • Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Item Details
Product Name Ethyl 2,2-Difluoro-2-(2-Pyridyl)Acetate
CAS No. 267876-28-8
Molecular Formula C9H9F2NO2
Molecular Weight 201.17 g/mol
Synonyms 2-Pyridineacetic acid, 2,2-difluoro-, ethyl ester; Ethyl 2,2-difluoro-2-(pyridin-2-yl)acetate; 2,2-Difluoro-2-(2-pyridyl)acetic acid ethyl ester; Difluoro(pyridin-2-yl)acetic acid ethyl ester; Ethyl α,α-difluoro-2-pyridylacetate
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Quality Control

Our Ethyl 2,2-Difluoro-2-(2-Pyridyl)Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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