Description

2-Chloro-6-(2-Pyridylthio)Isonicotinonitrile is a high-value heterocyclic building block and pharmaceutical intermediate. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate functionalized pyridine and isonicotinonitrile motifs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of novel pesticides and herbicides due to its functionalized pyridine core.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: A starting material for constructing organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name	2-Chloro-6-(2-Pyridylthio)Isonicotinonitrile
CAS No.	266337-47-7
Molecular Formula	C11H6ClN3S
Molecular Weight	247.70 g/mol
Synonyms	6-Chloro-2-[(pyridin-2-yl)sulfanyl]pyridine-4-carbonitrile; 2-Chloro-6-(pyridin-2-ylsulfanyl)isonicotinonitrile; 2-Chloro-6-(2-pyridylthio)-4-pyridinecarbonitrile; 4-Pyridinecarbonitrile, 2-chloro-6-[(2-pyridinyl)thio]-; 2-Chloro-6-(2-pyridinylthio)isonicotinonitrile; 2-Pyridylthio-substituted Chloroisonicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(2-Pyridylthio)Isonicotinonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.