Description

Isocyano(4-Methoxyphenyl)Methyl-4-Methylphenyl Sulfone is a specialized organic building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a versatile isocyanide reagent, enabling the construction of complex molecular architectures through multicomponent reactions. Pharmaceutical, agrochemical, and material science research and development teams need it for creating novel heterocycles, ligands, and functional polymers. Its unique sulfone and methoxy-substituted structure offers distinct electronic properties for fine-tuning reaction outcomes and material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for libraries of nitrogen-containing heterocycles via Passerini or Ugi-type multicomponent reactions.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection, leveraging its isocyano group for creating diverse bioactive scaffolds.
• Material Science & Polymer Chemistry: Used as a functional monomer or cross-linking agent in the design of advanced polymers, coatings, and resins with tailored properties.
• Catalyst & Ligand Synthesis: Acts as a building block for constructing sophisticated ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Chemical Biology & Probe Development: Utilized in bio-conjugation and the creation of chemical probes for studying biological processes due to its reactive isocyanide functionality.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new reaction pathways in organic synthesis laboratories.

Basic Information

Item	Details
Product Name	Isocyano(4-Methoxyphenyl)Methyl-4-Methylphenyl Sulfone
CAS No.	263389-54-4
Molecular Formula	C16H15NO3S
Molecular Weight	301.36 g/mol
Synonyms	1-Isocyano-1-(4-methoxyphenyl)-4-methylphenyl sulfone; [(4-Methoxyphenyl)(isocyano)methyl](4-methylphenyl) sulfone; 4-Methyl-α-isocyano-4'-methoxybenzhydryl sulfone; p-Tolyl [(4-methoxyphenyl)(isocyano)methyl] sulfone; Isocyanomethane derivative with sulfone linkage; Isocyanide sulfone building block; 4-Methoxy-α-isocyano-4'-methylbenzhydryl sulfone
EINECS	Contact for details

Quality Control

Every batch of Isocyano(4-Methoxyphenyl)Methyl-4-Methylphenyl Sulfone is produced and tested under a strict quality management system to ensure high purity, consistency, and reliability for your critical R&D and scale-up processes. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability, as isocyanides can be sensitive to moisture and oxidation over extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.