Description

1-(3,4-Dichlorophenyl)-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a reactive isocyanide functional group. This compound is valued for its role as a key intermediate in the synthesis of complex heterocyclic frameworks and pharmaceutical candidates. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as multicomponent reactions and ligand synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides.
• Multicomponent Reaction (MCR) Chemistry: Serves as a versatile reagent in Passerini and Ugi-type reactions to create diverse molecular libraries.
• Heterocyclic Compound Synthesis: Employed in the construction of complex nitrogen-containing heterocycles important in medicinal chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Material Science Research: Acts as a precursor for functionalized polymers and advanced organic materials.

Basic Information

Product Name	1-(3,4-Dichlorophenyl)-1-Tosylmethyl Isocyanide
CAS No.	263389-52-2
Molecular Formula	C15H11Cl2NO2S
Molecular Weight	340.22 g/mol
Synonyms	1-(3,4-Dichlorophenyl)-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-(3,4-Dichlorophenyl)-1-(p-tolylsulfonyl)methyl isocyanide; 1-(3,4-Dichlorophenyl)-1-(tosylmethyl)isocyanide; 1-(3,4-Dichlorophenyl)-1-(4-methylbenzenesulfonyl)methyl isocyanide; 1-Isocyano-1-(3,4-dichlorophenyl)-1-(p-toluenesulfonyl)methane; 1-(3,4-Dichlorophenyl)-1-(p-toluenesulfonylmethyl)isocyanide
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dichlorophenyl)-1-Tosylmethyl Isocyanide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of the compound, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.