Description

1-[Isocyano-(Toluene-4-Sulfonyl)-Methyl]-Naphthalene is a specialized organic building block featuring a unique isocyano and tosylmethyl functional group architecture. This compound is of significant value in advanced organic synthesis, particularly for the construction of complex heterocyclic frameworks and functionalized molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and novel compound library generation.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those containing naphthalene or sulfonamide motifs.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Material Science: Employed in the research and development of advanced organic materials, including polymers and liquid crystals.
• Chemical Biology Probes: Acts as a versatile scaffold for creating isocyanide-based probes used in bioorthogonal chemistry and target identification.
• Academic & Industrial R&D: A valuable reagent for methodology development in organic chemistry, particularly in multicomponent reactions (MCRs) and catalysis studies.
• Custom Synthesis: Used by fine chemical manufacturers for the contract synthesis of bespoke, high-value compounds for client projects.

Basic Information

Product Name	1-[Isocyano-(Toluene-4-Sulfonyl)-Methyl]-Naphthalene
CAS No.	263389-18-0
Molecular Formula	C19H15NO2S
Molecular Weight	321.39 g/mol
Synonyms	1-[(Isocyanomethyl)sulfonyl]-4-methylbenzene; 1-Isocyano-1-(p-tolylsulfonyl)methylnaphthalene; Naphthalene, 1-[isocyano[(4-methylphenyl)sulfonyl]methyl]-; TosMIC Naphthalene Derivative; p-Toluenesulfonylmethyl isocyanide naphthyl derivative; 1-((Isocyano)(tosyl)methyl)naphthalene; 1-(Isocyanotosylmethyl)naphthalene
EINECS	Contact for details

Quality Control

Our 1-[Isocyano-(Toluene-4-Sulfonyl)-Methyl]-Naphthalene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to meet the stringent requirements of research and development applications across global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintain at temperatures between 2°C and 8°C under an inert atmosphere. The compound is moisture-sensitive and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.