Description

Ethyl 4-(2-Iodophenyl)-4-Oxobutyrate is a high-purity organic building block featuring a reactive oxobutyrate ester and an iodophenyl moiety, making it a versatile intermediate for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, enabling the construction of complex molecular architectures. It is primarily sought by fine chemical manufacturers and R&D laboratories engaged in developing active pharmaceutical ingredients (APIs) and novel organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive iodine atom, and in cyclization reactions via the keto-ester functionality.
• Agrochemical Research: Serves as an intermediate in the development of new-generation herbicides and plant growth regulators.
• Material Science: Used in the research of organic semiconductors and liquid crystals due to its conjugated aromatic structure.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) settings.

Basic Information

Product Name	Ethyl 4-(2-Iodophenyl)-4-Oxobutyrate
CAS No.	263273-52-5
Molecular Formula	C12H13IO3
Molecular Weight	332.14 g/mol
Synonyms	Ethyl 4-(2-iodophenyl)-4-oxobutanoate; 4-(2-Iodophenyl)-4-oxobutyric Acid Ethyl Ester; 2-Iodobenzoylacetic Acid Ethyl Ester; Ethyl (2-Iodobenzoyl)acetate; Butanoic acid, 4-(2-iodophenyl)-4-oxo-, ethyl ester; Ethyl 4-oxo-4-(2-iodophenyl)butyrate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2-Iodophenyl)-4-Oxobutyrate is manufactured under a strict quality management system. Every batch is analyzed to ensure high chemical purity and consistency, with specifications tailored to meet the rigorous demands of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.