Description

5-Bromo-3-Pyridinecarboxylic Acid tert-Butyl Ester is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a protected carboxylic acid functional group for constructing complex heterocyclic molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical research.

Basic Information

Product Name	5-Bromo-3-Pyridinecarboxylic Acid tert-Butyl Ester
CAS No.	263270-02-6
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	tert-Butyl 5-bromonicotinate; 5-Bromo-3-pyridinecarboxylic acid tert-butyl ester; 5-Bromonicotinic acid tert-butyl ester; 3-Pyridinecarboxylic acid, 5-bromo-, 1,1-dimethylethyl ester; 5-Bromo-3-(tert-butoxycarbonyl)pyridine; Nicotinic acid, 5-bromo-, tert-butyl ester; tert-Butyl 5-bromopyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Pyridinecarboxylic Acid tert-Butyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.