Description

Torcetrapib is a potent and selective inhibitor of cholesteryl ester transfer protein (CETP). This compound is of significant interest in pharmaceutical research for its potential role in modulating lipid profiles and cardiovascular health. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents for dyslipidemia and atherosclerosis. Torcetrapib CAS NO 262352-17-0 represents a critical research-grade chemical for advancing metabolic and cardiovascular drug discovery.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the discovery and development of CETP inhibitors for cardiovascular disease.
• Biochemical Assays: Used as a selective tool compound in in vitro and ex vivo studies to investigate CETP function and lipid metabolism pathways.
• Preclinical Studies: Employed in animal models to evaluate the pharmacokinetics, pharmacodynamics, and efficacy of CETP-modulating therapies.
• Mechanism of Action Studies: Serves as a critical reagent for understanding the structure-activity relationship (SAR) of CETP inhibitors.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical substances.

Basic Information

Product Name	Torcetrapib
CAS No.	262352-17-0
Molecular Formula	C₂₆H₂₅F₉N₂O₄
Molecular Weight	600.48 g/mol
Synonyms	CP-529,414; 4-[[(1S,2S)-2-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-1-(4-fluorophenyl)cyclopentyl]methoxy]-3,5-dimethylbenzonitrile; 1,1-Dimethylethyl 6-[[(1S,2S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(4-fluorophenyl)cyclopentyl]methoxy]-2,4-dimethyl-3-pyridinecarboxylate; CP 529414; Torcetrapibum; Torcetrapib (CP-529,414)
EINECS	Contact for details

Quality Control

Our Torcetrapib is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We adhere to relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.