Description

Methyl 3-Amino-5-Bromo-4-Hydroxybenzoate is a high-purity, multi-functional benzoate derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring amino, bromo, and hydroxy substituents, makes it an invaluable intermediate for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and high-value compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its halogen and amino groups for bioactivity.
• Dye and Pigment Manufacturing: Serves as a core structure for synthesizing advanced organic dyes, pigments, and optical brighteners due to its conjugated aromatic system.
• Ligand and Catalyst Development: Employed in creating specialized ligands for metal catalysis and asymmetric synthesis, useful in fine chemical production.
• Material Science Research: Building block for organic semiconductors, liquid crystals, and polymers requiring specific electronic and steric properties.
• Academic and R&D Laboratories: Used in medicinal chemistry programs and methodological studies for constructing complex heterocycles and functionalized aromatics.

Basic Information

Item	Details
Product Name	Methyl 3-Amino-5-Bromo-4-Hydroxybenzoate
CAS No.	260249-10-3
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	Methyl 3-amino-5-bromo-4-hydroxybenzoate; 3-Amino-5-bromo-4-hydroxybenzoic acid methyl ester; 5-Bromo-4-hydroxy-3-aminobenzoic acid methyl ester; Methyl 5-bromo-4-hydroxy-3-aminobenzoate; Benzoic acid, 3-amino-5-bromo-4-hydroxy-, methyl ester; 260249-10-3; 3-Amino-5-bromo-4-hydroxy-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-5-Bromo-4-Hydroxybenzoate is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.