Description

(1R, 2R, 5S)-Neomenthyl Azide CAS NO 259826-43-2 is a high-purity, chiral azide derivative of neomenthol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its well-defined stereochemistry, which is essential for imparting specific three-dimensional structure and biological activity to target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical control is paramount.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the synthesis of chiral amines, triazoles, and other heterocycles via click chemistry (CuAAC) or Staudinger reduction, used in API development.
• Agrochemical Research & Development: Used to create chiral active ingredients for herbicides, fungicides, and pesticides with potentially enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science & Polymer Chemistry: Incorporated into polymers and dendrimers to introduce specific functional groups or modify material properties through azide-alkyne cycloaddition.
• Bioconjugation & Probe Synthesis: Utilized in chemical biology for labeling biomolecules (proteins, nucleic acids) or creating diagnostic probes due to its bio-orthogonal reactivity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and the discovery of new synthetic pathways.

Basic Information

Product Name	(1R, 2R, 5S)-Neomenthyl Azide
CAS No.	259826-43-2
Molecular Formula	C₁₀H₁₉N₃
Molecular Weight	181.28 g/mol
Synonyms	(1R,2R,5S)-2-Isopropyl-5-methylcyclohexyl Azide; (-)-Neomenthyl Azide; (1R,2R,5S)-Neomenthol Azide; (1R,2R,5S)-1-Azido-2-isopropyl-5-methylcyclohexane; Azidoneomenthol; Neomenthyl Azide; (1R,2R,5S)-Azidoneomenthol
EINECS	Contact for details

Quality Control

Our (1R, 2R, 5S)-Neomenthyl Azide is produced under strict quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC-MS, to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound should be handled with care, away from strong reducing agents and heat sources, in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.