Description

tert-Butyl (R)-2-(Azidomethyl)-1-Pyrrolidinecarboxylate is a high-purity chiral building block and key synthetic intermediate. This compound is of significant value for the development of novel pharmaceuticals and bioactive molecules due to its reactive azide and protected amine functionalities. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small-molecule therapeutics.
• Peptidomimetics Research: Used to introduce constrained pyrrolidine scaffolds and azide handles for "click chemistry" in drug discovery.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex, enantiomerically pure molecules in organic chemistry.
• Chemical Biology Probes: The azide group enables bioorthogonal conjugation for labeling and studying biological systems.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced, chiral crop protection agents.
• Academic & Industrial R&D: Fundamental building block for methodological development and exploring new chemical spaces.

Basic Information

Product Name	tert-Butyl (R)-2-(Azidomethyl)-1-Pyrrolidinecarboxylate
CAS No.	259537-91-2
Molecular Formula	C10H18N4O2
Molecular Weight	226.28 g/mol
Synonyms	(R)-1-Boc-2-(azidomethyl)pyrrolidine; (R)-tert-Butyl 2-(azidomethyl)pyrrolidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-(azidomethyl)-(R)-pyrrolidine; (R)-2-(Azidomethyl)-1-(tert-butoxycarbonyl)pyrrolidine; (R)-N-Boc-2-(azidomethyl)pyrrolidine; (R)-1-N-Boc-2-(azidomethyl)pyrrolidine; tert-Butyl (2R)-2-(azidomethyl)-1-pyrrolidinecarboxylate; (R)-1-Boc-2-azidomethylpyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (R)-2-(Azidomethyl)-1-Pyrrolidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept tightly sealed in a desiccated environment after opening to prevent moisture uptake and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.