Description

Spiro[2.2]Pentanecarboxylic Acid, 1-Amino-, (1R)- (9Ci) is a high-purity, chiral spirocyclic building block of significant interest in advanced organic synthesis. Its unique constrained three-dimensional structure and stereochemistry make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• As a key chiral intermediate in the synthesis of novel pharmaceutical candidates, particularly for central nervous system (CNS) and antiviral targets.
• Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its rigid, three-dimensional scaffold.
• Employed as a specialized building block in asymmetric synthesis for creating compounds with high stereochemical complexity.
• Serves as a precursor for ligand and catalyst development in transition metal-catalyzed reactions.
• Used in agrochemical research for the development of new herbicides and pesticides with novel modes of action.
• Applied in academic and institutional research exploring new spirocyclic chemistry and its physicochemical properties.

Basic Information

Product Name	Spiro[2.2]Pentanecarboxylic Acid, 1-Amino-, (1R)- (9Ci)
CAS No.	259097-27-3
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	(1R)-1-Aminospiro[2.2]pentane-1-carboxylic acid; (R)-1-Aminospiro[2.2]pentane-1-carboxylic acid; (1R)-1-Amino-1-carboxyspiro[2.2]pentane; (R)-1-Amino-1-carboxyspiro[2.2]pentane; (R)-1-Aminospiro[2.2]pentane-1-carboxylic Acid; (1R)-1-Aminospiro[2.2]pentane-1-carboxylic Acid; Spiro[2.2]pentane-1-carboxylic acid, 1-amino-, (1R)-; (R)-Spiro[2.2]pentanecarboxylic acid, 1-amino-
EINECS	Contact for details

Quality Control

Our Spiro[2.2]Pentanecarboxylic Acid, 1-Amino-, (1R)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical data. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥97% by HPLC), chiral purity (typically ≥99% ee), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.