Description

Imidazo[5,1-B]Thiazole, 3-(Azidomethyl)- is a specialized heterocyclic organic compound featuring a fused imidazole-thiazole core with a reactive azidomethyl functional group. This unique structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for click chemistry applications. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or central nervous system disorders.
• Click Chemistry Reagent: The azide group enables efficient Huisgen 1,3-dipolar cycloaddition reactions with alkynes, facilitating the rapid assembly of complex molecular architectures for drug discovery and bioconjugation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the biological activity of the imidazothiazole scaffold.
• Polymer & Materials Science: Acts as a functional monomer or cross-linking agent for creating smart polymers, hydrogels, or surface coatings with specific responsive properties.
• Chemical Biology Probe Synthesis: Employed to tag biomolecules (proteins, nucleic acids) for imaging, diagnostic, or therapeutic purposes via bioorthogonal chemistry.
• Ligand & Catalyst Development: The nitrogen-rich heterocycle can be utilized to construct novel ligands for metal catalysis or as a core structure in organocatalysts.

Basic Information

Item	Details
Product Name	Imidazo[5,1-B]Thiazole, 3-(Azidomethyl)-
CAS No.	258839-60-0
Molecular Formula	C6H5N5S
Molecular Weight	179.20 g/mol
Synonyms	3-(Azidomethyl)imidazo[5,1-b]thiazole; 3-Azidomethylimidazo[5,1-b]thiazole; Imidazo[5,1-b]thiazole, 3-(azidomethyl)-; Azidomethylimidazothiazole; 258839-60-0; 3-(Azidomethyl)-imidazo[5,1-b]thiazole
EINECS	Contact for details

Quality Control

Our Imidazo[5,1-B]Thiazole, 3-(Azidomethyl)- is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.