Description

Methyl 6-Methyl-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine-3-Acetate is a high-purity, advanced pharmaceutical intermediate belonging to the imidazopyridine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates, especially within the imidazopyridine scaffold.
• API Synthesis: Serves as a core structural unit for constructing complex molecules with potential pharmacological activity in pre-clinical and clinical research.
• Medicinal Chemistry Research: Used by R&D laboratories for structure-activity relationship (SAR) studies and lead optimization processes.
• Contract Manufacturing: Supplied to CDMOs for scale-up production under current Good Manufacturing Practice (cGMP) conditions for clinical trial material.
• Biochemical Research: Employed as a standard or reference compound in analytical method development and validation.

Basic Information

Item	Details
Product Name	Methyl 6-Methyl-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine-3-Acetate
CAS No.	258273-50-6
Molecular Formula	C18H18N2O2
Molecular Weight	294.35 g/mol
Synonyms	Methyl 2-(p-tolyl)-6-methylimidazo[1,2-a]pyridine-3-acetate; 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetic acid methyl ester; Methyl (6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl)acetate; Imidazo[1,2-a]pyridine-3-acetic acid, 6-methyl-2-(4-methylphenyl)-, methyl ester; CAS 258273-50-6
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Methyl-2-(4-Methylphenyl)Imidazo[1,2-A]Pyridine-3-Acetate adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.