Description

8,8'-(1,4-Butanediyl)Bis-8-Azaspiro[4.5]Decane-7,9-Dione is a high-purity, specialized organic compound belonging to the bis-spirocyclic diketone class, serving as a critical advanced intermediate in sophisticated chemical synthesis. Its unique molecular architecture, featuring dual spirocyclic and diketone functionalities, provides a versatile and rigid scaffold for constructing complex molecules with precise stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is utilized in the synthesis of novel active ingredients, as well as in advanced material science for creating specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways, leveraging its complex, constrained structure.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its spirocyclic core can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Advanced Material Science: Employed in the development of specialty polymers, dendrimers, and supramolecular structures that require rigid, three-dimensional building blocks.
• Chemical Research & Development: A valuable tool for academic and industrial R&D focused on exploring new chemical spaces and reaction methodologies involving polycyclic systems.
• Fine Chemical Production: Acts as a high-value intermediate in the custom synthesis of complex fine chemicals for various high-tech industries.

Basic Information

Product Name	8,8'-(1,4-Butanediyl)Bis-8-Azaspiro[4.5]Decane-7,9-Dione
CAS No.	257877-44-4
Molecular Formula	C21H30N2O4
Molecular Weight	374.48 g/mol
Synonyms	1,1'-(Butane-1,4-diyl)bis(8-azaspiro[4.5]decane-7,9-dione); Bis(8-azaspiro[4.5]decane-7,9-dione), 1,1'-(1,4-butanediyl)-; 8,8'-(Butane-1,4-diyl)bis(8-azaspiro[4.5]decane-7,9-dione); 8-Azaspiro[4.5]decane-7,9-dione, 8,8'-(1,4- butanediyl)bis-; 257877-44-4; Butanediyl-bis-8-azaspiro[4.5]decane-7,9-dione
EINECS	Contact for details

Quality Control

Our production of 8,8'-(1,4-Butanediyl)Bis-8-Azaspiro[4.5]Decane-7,9-Dione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles. We support cGMP-compliant manufacturing for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.