Description

3-(4-Chlorophenoxy)-5-(Trifluoromethyl)-2-Pyridinecarbonitrile is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of novel active ingredients, particularly in the agrochemical and pharmaceutical sectors, due to its unique trifluoromethyl and chlorophenoxy substituents. It is primarily sought by R&D chemists and process development scientists in fine chemical, agrochemical, and pharmaceutical manufacturing for creating new molecules with enhanced biological activity and physical properties.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Pharmaceutical Intermediate: Used in medicinal chemistry research for the development of active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, or organic electronic materials with specific optical or electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions and as a versatile scaffold for constructing complex polycyclic structures in organic synthesis laboratories.

Basic Information

Product Name	3-(4-Chlorophenoxy)-5-(Trifluoromethyl)-2-Pyridinecarbonitrile
CAS No.	256658-19-2
Molecular Formula	C13H6ClF3N2O
Molecular Weight	298.65 g/mol
Synonyms	5-(Trifluoromethyl)-3-(4-chlorophenoxy)picolinonitrile; 3-(p-Chlorophenoxy)-5-(trifluoromethyl)-2-pyridinecarbonitrile; 2-Cyano-3-(4-chlorophenoxy)-5-(trifluoromethyl)pyridine; 256658-19-2; 3-(4-Chlorophenoxy)-5-(trifluoromethyl)picolinonitrile; 5-Trifluoromethyl-3-(4-chlorophenoxy)-2-cyanopyridine
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenoxy)-5-(Trifluoromethyl)-2-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.