Description

Methyl 5-Iodo-2-[(Mesitylsulfonyl)Oxy]Benzenecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its mesitylsulfonyl (mesyl) and iodo functional groups. This compound is critical for facilitating key synthetic transformations, particularly in the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science: Acts as a monomer or cross-linking agent in the research of advanced polymers with specific electronic or thermal properties.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for carbon-carbon bond formation due to the reactive iodo substituent.
• Chemical Biology: Utilized as a probe or labeling reagent in biochemical research to study protein interactions and enzyme mechanisms.
• Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry at universities and CROs (Contract Research Organizations).

Basic Information

Product Name	Methyl 5-Iodo-2-[(Mesitylsulfonyl)Oxy]Benzenecarboxylate
CAS No.	256521-67-2
Molecular Formula	C17H17IO5S
Molecular Weight	460.28 g/mol
Synonyms	Methyl 5-iodo-2-[(2,4,6-trimethylphenyl)sulfonyl]oxybenzoate; 5-Iodo-2-[(mesitylsulfonyl)oxy]benzoic Acid Methyl Ester; Benzoic acid, 5-iodo-2-[(2,4,6-trimethylphenyl)sulfonyl]oxy-, methyl ester; Methyl 5-iodosalicylate mesylate derivative; 2-Hydroxy-5-iodobenzoic acid methyl ester mesylate; Mesitylenesulfonic acid, 5-iodo-2-(methoxycarbonyl)phenyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Iodo-2-[(Mesitylsulfonyl)Oxy]Benzenecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.