Description

Pyridine, 5-Bromo-2-Isocyano- (9Ci) is a specialized heterocyclic building block featuring both bromo and isocyano functional groups on a pyridine core. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical researchers for constructing novel active ingredients and functional materials. The compound's reactivity profile allows for selective modifications, enabling the creation of targeted chemical libraries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogen and isonitrile groups for structure-activity relationship (SAR) studies.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient pyridine ring.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, where the isocyano group can facilitate bioconjugation.

Basic Information

Product Name	Pyridine, 5-Bromo-2-Isocyano- (9Ci)
CAS No.	255842-13-8
Molecular Formula	C7H3BrN2
Molecular Weight	195.02 g/mol
Synonyms	5-Bromo-2-isocyanopyridine; 2-Isocyano-5-bromopyridine; 5-Bromo-2-pyridyl isocyanide; 5-Bromopyridine-2-carbonitrile (common misnomer, note: isocyanide differs from nitrile); 5-Bromo-2-isocyano-pyridine; 2-Pyridinecarbonitrile, 5-bromo- (related); 255842-13-8 (CAS); 5-Bromo-2-(isocyano)pyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 5-Bromo-2-Isocyano- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications. For custom synthesis or specific grade requirements, our technical team is available for consultation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture ingress. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.