Description

n-(2-Hydroxyethyl)-11-Azaartemisinin is a chemically modified derivative of the potent antimalarial natural product artemisinin. This compound is significant for its role as a key synthetic intermediate in the development of novel artemisinin-based therapeutics and research compounds. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing next-generation antiparasitic and anticancer agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel artemisinin-derived drugs with potential enhanced efficacy or reduced resistance.
• Antimalarial Research: Used in biological and pharmacological studies to investigate structure-activity relationships (SAR) of artemisinin analogs.
• Anticancer Agent Development: Serves as a precursor in the research of artemisinin-based compounds for their cytotoxic properties against various cancer cell lines.
• Chemical Biology Probes: Utilized in the design of molecular probes to study the mechanism of action of artemisinin and its derivatives.
• Medicinal Chemistry: A versatile scaffold for the synthesis of new chemical entities (NCEs) targeting parasitic and other diseases.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	n-(2-Hydroxyethyl)-11-Azaartemisinin
CAS No.	255731-00-1
Molecular Formula	C17H27NO6
Molecular Weight	341.40 g/mol
Synonyms	11-Azaartemisinin, 2-hydroxyethyl derivative; 11-Aza-9-desmethylartemisinin, N-(2-hydroxyethyl)-; 11-N-(2-Hydroxyethyl)artemisinin; 11-Aza-artemisinin hydroxyethyl derivative; Artemisinin, 11-aza-, N-(2-hydroxyethyl)-; 255731-00-1; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-[(2-Hydroxyethyl)amino]-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxyethyl)-11-Azaartemisinin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.