Description

Methyl (2S)-2-Amino-3-(3-Cyanophenyl)Propanoate is a high-purity, non-natural amino acid ester derivative characterized by its chiral center and functionalized aromatic side chain. This compound serves as a critical chiral building block and intermediate in sophisticated organic synthesis, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical development teams focused on creating novel active pharmaceutical ingredients (APIs), peptide mimetics, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Peptidomimetics & Constrained Peptide Synthesis: Used to incorporate a rigid, cyanophenyl-containing side chain into peptide backbones to enhance metabolic stability and receptor binding affinity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology & Proteomics: Serves as a building block for designing activity-based probes, molecular tags, and other chemical tools for studying biological systems.
• Agrochemical Research: Potential intermediate in the synthesis of advanced, chiral crop protection agents and herbicides.
• Material Science: Can be utilized in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	Methyl (2S)-2-Amino-3-(3-Cyanophenyl)Propanoate
CAS No.	255374-78-8
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	(S)-Methyl 2-amino-3-(3-cyanophenyl)propanoate; L-3-Cyanophenylalanine methyl ester; Methyl L-β-(3-cyanophenyl)-α-alaninate; (2S)-2-Amino-3-(3-cyanophenyl)propanoic acid methyl ester; Methyl (S)-2-amino-3-(3-cyanophenyl)propionate; 3-Cyano-L-phenylalanine methyl ester; (S)-3-(3-Cyanophenyl)alanine methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (2S)-2-Amino-3-(3-Cyanophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.