Description

Tasquinimod is a potent and selective oral immunomodulatory agent with significant research and development interest. Its primary value lies in its targeted mechanism of action, which modulates the tumor microenvironment and shows promise in oncology applications. This compound is essential for pharmaceutical R&D teams, academic researchers, and clinical trial sponsors focused on developing novel cancer therapeutics, particularly for castration-resistant prostate cancer and other solid tumors.

Application

• Oncology Research & Drug Development: A key investigational compound for preclinical and clinical studies targeting various cancers.
• Immunomodulation Studies: Used in research to understand and manipulate immune responses within the tumor microenvironment.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Mechanistic Biology Research: Employed to study the role of S100A9 and other molecular pathways in disease progression.
• Clinical Trial Material (CTM): Supplied as a critical raw material for the formulation of drug products used in human clinical trials.

Basic Information

Product Name	Tasquinimod
CAS No.	254964-60-8
Molecular Formula	C₂₀H₁₉N₃O₄
Molecular Weight	365.39 g/mol
Synonyms	ABR-215050; Tasquinimod hydrate; 4-Hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-1,2-dihydroquinoline-3-carboxamide; ABR 215050; UNII-6S1P3S3TRE; 6S1P3S3TRE; CC-952; LS-192783
EINECS	Contact for details

Quality Control

Our Tasquinimod is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.