Description

tert-Butyl-n-Succinimidyl N N'-Ethylene- is a specialized chemical intermediate, primarily used as a reactive linker or coupling agent in advanced organic synthesis. Its value lies in its ability to facilitate the formation of stable amide bonds under mild conditions, which is critical for constructing complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and bioconjugation sectors, particularly for developing active pharmaceutical ingredients (APIs), peptide modifications, and labeled biomolecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation Reagent: Used for coupling peptides, proteins, or antibodies with reporter molecules, drugs, or polymers.
• Cross-linking Agent: Facilitates the formation of stable bridges between amine-containing molecules in material science and polymer chemistry.
• Proteomics Research: Employed in chemical proteomics for labeling and enriching target proteins for study.
• Diagnostic Reagent Synthesis: Integral in creating components for diagnostic assays and imaging agents.
• Solid-Phase Peptide Synthesis (SPPS): Acts as an activating agent for coupling amino acids during peptide chain assembly.

Basic Information

Product Name	tert-Butyl-n-Succinimidyl N N'-Ethylene-
CAS No.	254100-95-3
Molecular Formula	C10H16N2O4
Molecular Weight	228.25 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-N'-(succinimidyloxycarbonyl)ethylenediamine; Boc-NH-(CH2)2-NH-O-CO-O-Su; 1-[(tert-Butoxycarbonyl)amino]-3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl; tert-Butyl N-[2-[[(2,5-dioxopyrrolidin-1-yl)oxy]carbonylamino]ethyl]carbamate; Boc-EDA-OSu; Boc-Ethylenediamine-NHS ester; N-Boc-ethylenediamine, N-hydroxysuccinimide ester; Nα-Boc-ethylenediamine NHS ester
EINECS	Contact for details

Quality Control

Our tert-Butyl-n-Succinimidyl N N'-Ethylene- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with high-purity standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.