Description

tert-Butyl 2-Methyl-6-Oxopiperidine-1-Carboxylate is a high-purity, protected piperidone derivative serving as a critical chiral building block and advanced pharmaceutical intermediate. This compound is essential for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and process development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used for constructing complex heterocyclic frameworks and introducing the 2-methyl-6-oxopiperidine moiety into target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its defined stereochemistry and functional groups.
• Process Chemistry & Scale-Up: Serves as a validated intermediate for the development and optimization of scalable, GMP-compliant manufacturing routes for APIs.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of specialized compounds for agrochemical and material science applications.

Basic Information

Product Name	tert-Butyl 2-Methyl-6-Oxopiperidine-1-Carboxylate
CAS No.	253866-57-8
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	1-Boc-2-methyl-6-piperidone; 1-(tert-Butoxycarbonyl)-2-methylpiperidin-6-one; 2-Methyl-6-oxopiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 2-methyl-6-oxo-1-piperidinecarboxylate; 2-Methyl-1-(tert-butoxycarbonyl)piperidin-6-one; 1-Boc-2-methyl-1,2,3,6-tetrahydropyridin-2-one; N-Boc-2-methyl-6-piperidone
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methyl-6-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.