Description

Pyridine, 3-Methoxy-2-[(Trimethylsilyl)Oxy]- (9Ci) is a specialized organosilicon-protected pyridine derivative, serving as a valuable synthetic intermediate. This compound is designed to provide chemoselectivity and stability in complex organic transformations, particularly in the construction of heterocyclic and pharmaceutical scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those containing functionalized pyridine or dihydropyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its protected hydroxyl functionality.
• Organometallic Chemistry: Acts as a ligand precursor or a protected directing group in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic semiconductors and liquid crystals due to its modified pyridine structure.
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic synthesis and total synthesis projects.

Basic Information

Product Name	Pyridine, 3-Methoxy-2-[(Trimethylsilyl)Oxy]- (9Ci)
CAS No.	252980-61-3
Molecular Formula	C9H15NO2Si
Molecular Weight	197.31 g/mol
Synonyms	2-[(Trimethylsilyl)oxy]-3-methoxypyridine; 3-Methoxy-2-(trimethylsiloxy)pyridine; 3-Methoxy-2-(trimethylsilyloxy)pyridine; 2-(Trimethylsiloxy)-3-methoxypyridine; Pyridine, 3-methoxy-2-[(trimethylsilyl)oxy]-; TMS-protected 3-methoxy-2-hydroxypyridine; 3-Methoxypyridin-2-yloxytrimethylsilane
EINECS	Contact for details

Quality Control

Our Pyridine, 3-Methoxy-2-[(Trimethylsilyl)Oxy]- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.