Description

Ethyl 3-Oxo-3-(4-(Trifluoromethoxy)Phenyl)Propanoate is a high-purity organic ester building block featuring a trifluoromethoxy-substituted aromatic ketone moiety. This compound is valued for its role as a versatile synthetic intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and insecticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with tailored properties for coatings, adhesives, and high-performance materials.
• Chemical Research & Development: A crucial reagent in academic and industrial labs for exploring new organic reactions and methodologies, such as Claisen condensations and Michael additions.
• Fluorine Chemistry Studies: Ideal substrate for investigating the influence of the trifluoromethoxy group on reaction kinetics and molecular properties in medicinal chemistry.

Basic Information

Product Name	Ethyl 3-Oxo-3-(4-(Trifluoromethoxy)Phenyl)Propanoate
CAS No.	252955-06-9
Molecular Formula	C₁₂H₁₁F₃O₄
Molecular Weight	276.21 g/mol
Synonyms	Ethyl 4-(Trifluoromethoxy)benzoylacetate; 3-Oxo-3-[4-(trifluoromethoxy)phenyl]propanoic Acid Ethyl Ester; Ethyl (4-Trifluoromethoxybenzoyl)acetate; 4-(Trifluoromethoxy)benzoylacetic Acid Ethyl Ester; Ethyl 3-Oxo-3-(p-(trifluoromethoxy)phenyl)propionate; TFMP-BzAA-OEt; 252955-06-9
EINECS	Contact for details

Quality Control

Our Ethyl 3-Oxo-3-(4-(Trifluoromethoxy)Phenyl)Propanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.