Description

1,2-Dihydro-2-Oxo-Spiro[3H-Indole-3,4'-Piperidine]-1'-Carboxylic Acid 1,1-Dimethylethyl Ester is a sophisticated spirocyclic indole derivative, a crucial building block in modern organic synthesis. Its complex, rigid molecular architecture makes it a highly valuable intermediate for constructing novel pharmacologically active compounds. This product is primarily targeted at research and development teams within the pharmaceutical and agrochemical industries, where it serves as a key precursor in the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents with specific biological activity.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular tools to study biological pathways and protein interactions.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and natural product analogs.
• Material Science Research: Potential precursor for specialty polymers or organic electronic materials due to its fused ring system.

Basic Information

Product Name	1,2-Dihydro-2-Oxo-Spiro[3H-Indole-3,4'-Piperidine]-1'-Carboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	252882-60-3
Molecular Formula	C17H20N2O3
Molecular Weight	300.35 g/mol
Synonyms	tert-Butyl 2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate; 1'-Boc-2-oxospiro[indoline-3,4'-piperidine]; 1,1-Dimethylethyl 1,2-dihydro-2-oxospiro[3H-indole-3,4'-piperidine]-1'-carboxylate; Spiro[indoline-3,4'-piperidine]-1'-carboxylic acid, 1,1-dimethylethyl ester, 2-oxo-; 2-Oxospiro[indoline-3,4'-piperidine]-1'-carboxylic acid tert-butyl ester; 1'-N-Boc-2-oxospiro[indoline-3,4'-piperidine]; Boc-protected 2-oxospiro[indoline-3,4'-piperidine]; 252882-60-3
EINECS	Contact for details

Quality Control

Our production of 1,2-Dihydro-2-Oxo-Spiro[3H-Indole-3,4'-Piperidine]-1'-Carboxylic Acid 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and organic solvents as indicated by its chemical properties. For long-term storage, consider inert atmosphere conditions to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.