Description

1H-Indole-1,2-Dicarboxylic Acid, 2,3-Dihydro-, 1-(1,1-Dimethylethyl) 2-(Phenylmethyl) Ester is a high-purity, synthetically valuable indole derivative. This compound serves as a crucial protected intermediate in advanced organic synthesis, particularly for constructing complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of indole-based drug candidates targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing novel herbicides and plant growth regulators that leverage the indole core structure.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex molecules via its reactive ester and protected carboxylic acid functionalities.
• Material Science Precursor: Potential monomer or intermediate for synthesizing specialized polymers and organic electronic materials.

Basic Information

Product Name	1H-Indole-1,2-Dicarboxylic Acid, 2,3-Dihydro-, 1-(1,1-Dimethylethyl) 2-(Phenylmethyl) Ester
CAS No.	252357-58-7
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	tert-Butyl benzyl 2,3-dihydro-1H-indole-1,2-dicarboxylate; 1-(tert-Butoxycarbonyl)-2-(benzyloxycarbonyl)-2,3-dihydro-1H-indole; 2,3-Dihydro-1H-indole-1,2-dicarboxylic acid 1-tert-butyl 2-benzyl ester; Benzyl 1-(tert-butoxycarbonyl)-2,3-dihydro-1H-indole-2-carboxylate; 1-Boc-2-Cbz-2,3-dihydroindole; N-Boc-2-Cbz-indoline; 1-N-Boc-2-N-Cbz-indoline; Protected Indoline-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), ensuring consistency for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Production follows cGMP guidelines where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.