Description

Spiro[4.4]Nonane-1-Carboxylic Acid, 4-Amino-7-Methyl- (9Ci) is a high-purity, functionalized spirocyclic compound of significant interest in advanced organic synthesis. This specialized chemical serves as a critical pharmacophore and chiral building block for the development of novel active pharmaceutical ingredients (APIs) and complex molecular architectures. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create molecules with unique three-dimensional properties and biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the spirocyclic structure can confer specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	Spiro[4.4]Nonane-1-Carboxylic Acid, 4-Amino-7-Methyl- (9Ci)
CAS No.	251461-91-3
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	4-Amino-7-methylspiro[4.4]nonane-1-carboxylic acid; 7-Methyl-4-aminospiro[4.4]nonane-1-carboxylic acid; 4-Amino-7-methyl-1-spiro[4.4]nonanecarboxylic acid; 1-Carboxy-4-amino-7-methylspiro[4.4]nonane; Spiro[4.4]nonane-1-carboxylic acid, 4-amino-7-methyl-; (4-Amino-7-methylspiro[4.4]nonan-1-yl)methanoic acid
EINECS	Contact for details

Quality Control

Our production of Spiro[4.4]Nonane-1-Carboxylic Acid, 4-Amino-7-Methyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support development and scale-up under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.