Description

Carbamic Acid, (3-Amino-2-Hydroxybutyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic compound with a protected amino and carbamate functional group, serving as a valuable building block in advanced organic synthesis. Its primary value lies in its role as a key chiral intermediate for the development of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular pathways. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and mimetics due to its amino acid-like structure with protected functionalities.
• Agrochemical Synthesis: Serves as a building block for creating advanced, chiral herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Utilized in the development of chiral ligands and catalysts for enantioselective synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Carbamic Acid, (3-Amino-2-Hydroxybutyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	251458-26-1
Molecular Formula	C9H20N2O3
Molecular Weight	204.27 g/mol
Synonyms	tert-Butyl (3-amino-2-hydroxybutyl)carbamate; N-(tert-Butoxycarbonyl)-3-amino-2-hydroxybutylamine; 3-Amino-2-hydroxybutylcarbamic acid tert-butyl ester; BOC-3-Amino-2-hydroxybutylamine; (3-Amino-2-hydroxybutyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-(3-amino-2-hydroxybutyl)carbamate; (R/S)-tert-Butyl (3-amino-2-hydroxybutyl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Amino-2-Hydroxybutyl)-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.