Description

Ethyl 1-Bromo-2,7-Naphthyridine-3-Carboxylate is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromine substituent and ester functionality, which enable precise molecular construction and diversification. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in constructing novel active ingredients for crop protection agents, leveraging the naphthyridine scaffold's bioactivity.
• Material Science: Serves as a monomer or functional unit in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive bromo group, facilitating bioconjugation and target identification studies.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for creating bespoke compound libraries for high-throughput screening.

Basic Information

Product Name	Ethyl 1-Bromo-2,7-Naphthyridine-3-Carboxylate
CAS No.	250674-54-5
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	1-Bromo-2,7-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate; 3-Ethoxycarbonyl-1-bromo-2,7-naphthyridine; 1-Bromo-3-(ethoxycarbonyl)-2,7-naphthyridine; 2,7-Naphthyridine-3-carboxylic acid, 1-bromo-, ethyl ester; 250674-54-5; Ethyl 1-bromo-2,7-naphthyridine-3-carboxylate CAS 250674-54-5
EINECS	Contact for details

Quality Control

Our Ethyl 1-Bromo-2,7-Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.