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3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide CAS NO 249566-73-2


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CAS No.:249566-73-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide is a high-purity, fluorinated carbohydrate derivative and a key synthetic intermediate in modern organic and medicinal chemistry. This compound matters for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly nucleoside analogs and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and novel diagnostic probes. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for critical applications.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel fluorinated nucleoside analogs with potential antiviral and anticancer activities.
  • Glycobiology Research: Used as a building block for constructing complex oligosaccharides and glycoconjugates to study carbohydrate-protein interactions.
  • Probe Development: Serves as a starting material for creating fluorescent or radiolabeled sugar analogs for diagnostic and imaging applications.
  • Chemical Biology: Employed in click chemistry reactions via its azide functional group for bioconjugation and activity-based protein profiling.
  • Process Chemistry: Utilized in scale-up routes for the production of active pharmaceutical ingredients (APIs) requiring fluorinated sugar moieties.
  • Academic Research: A valuable reagent for methodological development in synthetic organic chemistry, particularly in stereoselective glycosylation.

Basic Information

Item Detail
Product Name 3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide
CAS No. 249566-73-2
Molecular Formula C12H15FN3O7
Molecular Weight 332.26 g/mol
Synonyms 2-Deoxy-2-fluoro-3,4,6-tri-O-acetyl-β-D-glucopyranosyl azide; 2-Fluoro-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl azide; 1-Azido-2-fluoro-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranose; β-D-Glucopyranosyl azide, 2-deoxy-2-fluoro-3,4,6-tri-O-acetate; Triacetylfluoroglucosyl azide; 249566-73-2; 2-Fluoro-2-deoxyglucose triacetate azide
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Quality Control

Our 3,4,6-Tri-o-Acetyl-2-Deoxy-2-Fluoro-β-D-Glucopyranosyl Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under inert atmosphere when appropriate to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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