Description

3,4-Pyrrolidinediol, 2-(5,6-Diamino-3-Pyridinyl)-5-(Hydroxymethyl)-, (2S,3S,4R,5R)- is a high-purity, stereochemically defined pyrrolidine derivative of significant interest in advanced pharmaceutical research and development. This compound's complex structure, featuring multiple chiral centers and functional groups, makes it a valuable key intermediate or building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the discovery of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of complex drug candidates, especially in neurological and metabolic disorder research.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing biological pathways due to its structural similarity to natural products.
• Organic Synthesis: Acts as a versatile precursor for constructing nitrogen-containing heterocycles and functionalized pyrrolidine libraries for medicinal chemistry.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Asymmetric Catalysis: Potential use as a ligand or chiral auxiliary in catalytic asymmetric synthesis to induce stereoselectivity.

Basic Information

Item	Details
Product Name	3,4-Pyrrolidinediol, 2-(5,6-Diamino-3-Pyridinyl)-5-(Hydroxymethyl)-, (2S,3S,4R,5R)-
CAS No.	249503-27-3
Molecular Formula	C10H16N4O3
Molecular Weight	240.26 g/mol
Synonyms	(2S,3S,4R,5R)-2-(5,6-Diaminopyridin-3-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol; 2-(5,6-Diamino-3-pyridinyl)-5-(hydroxymethyl)-3,4-pyrrolidinediol, (2S,3S,4R,5R)-; 249503-27-3; (2S,3S,4R,5R)-2-(5,6-Diamino-3-pyridyl)-5-(hydroxymethyl)-3,4-dihydroxypyrrolidine; Pyrrolidine-3,4-diol, 2-(5,6-diamino-3-pyridinyl)-5-(hydroxymethyl)-, (2S,3S,4R,5R)-
EINECS	Contact for details

Quality Control

Our 3,4-Pyrrolidinediol, 2-(5,6-Diamino-3-Pyridinyl)-5-(Hydroxymethyl)-, (2S,3S,4R,5R)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines for analytical method validation, and specifications can be aligned with customer-specific requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.