Description

Butanedioic Acid, 2,3-Dihydroxy- (2R,3R)-, Bis(2,2,2-Trifluoroethyl) Ester is a high-value, chiral derivative of tartaric acid, specifically engineered for advanced synthetic applications. This compound matters for its role as a key chiral building block and resolving agent in the synthesis of complex, optically active pharmaceuticals and fine chemicals. Industries that require high-purity, enantiomerically pure intermediates, such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Chiral Resolution Agent: Used to separate racemic mixtures of amines, acids, and other compounds via diastereomeric salt formation or as a component of chiral stationary phases.
• Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in asymmetric catalysis, including hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Advanced Material Research: Utilized in the development of chiral polymers, liquid crystals, and other functional materials with specific optical properties.
• Fine Chemical Manufacturing: Acts as a key intermediate for flavors, fragrances, and other high-value specialty chemicals requiring defined stereochemistry.

Basic Information

Product Name	Butanedioic Acid, 2,3-Dihydroxy- (2R,3R)-, Bis(2,2,2-Trifluoroethyl) Ester
CAS No.	248914-80-9
Molecular Formula	C10H10F6O6
Molecular Weight	340.18 g/mol
Synonyms	(2R,3R)-2,3-Dihydroxybutanedioic Acid Bis(2,2,2-trifluoroethyl) Ester; L-(+)-Tartaric Acid Bis(2,2,2-Trifluoroethyl) Ester; (R,R)-Tartaric Acid Di(2,2,2-Trifluoroethyl) Ester; Bis(2,2,2-trifluoroethyl) (2R,3R)-2,3-dihydroxysuccinate; Di(2,2,2-trifluoroethyl) L-tartrate; 2,2,2-Trifluoroethyl (2R,3R)-2,3-dihydroxybutanedioate; L-Tartaric Acid Bis(trifluoroethyl) Ester
EINECS	Contact for details

Quality Control

Our Butanedioic Acid, 2,3-Dihydroxy- (2R,3R)-, Bis(2,2,2-Trifluoroethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.