Description

tert-Butyl 2-(4-bromophenylthio)-2-methylpropanoate is a specialized organic sulfur compound featuring a tert-butyl ester group and a brominated phenylthio moiety. This chemical serves as a valuable building block and intermediate in advanced organic synthesis, enabling the introduction of protected thioether functionalities. It is primarily utilized by pharmaceutical and agrochemical research & development teams for the construction of complex molecules, including potential active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting sulfur-containing bioactive molecules.
• Agrochemical Synthesis: Used in the production pathway for advanced pesticides, herbicides, and fungicides where the bromophenylthio group is a critical structural element.
• Material Science Research: Employed as a monomer or precursor in the synthesis of specialized polymers, ligands for catalysis, or advanced organic electronic materials.
• Chemical Biology Probes: Acts as a building block for creating biochemical tools and probes used to study enzyme mechanisms or cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	tert-Butyl 2-(4-Bromophenylthio)-2-Methylpropanoate
CAS No.	247923-30-4
Molecular Formula	C₁₄H₁₉BrO₂S
Molecular Weight	331.27 g/mol
Synonyms	2-(4-Bromophenylthio)-2-methylpropanoic acid tert-butyl ester; tert-Butyl 2-[(4-bromophenyl)thio]-2-methylpropanoate; 2-Methyl-2-[(4-bromophenyl)thio]propanoic acid 1,1-dimethylethyl ester; Propanoic acid, 2-[(4-bromophenyl)thio]-2-methyl-, 1,1-dimethylethyl ester; TB-BPTMP; 4-Bromophenyl tert-butyl thiomethylpropanoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(4-bromophenylthio)-2-methylpropanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.