Description

Cyclopropanecarboxylic Acid, 3-Ethenyl-2,2-Dimethyl-, Methyl Ester, (1S,3R)- is a high-purity, stereochemically defined chiral building block of significant synthetic value. This compound matters as a key intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its specific stereochemistry is crucial for biological activity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing molecules with precise three-dimensional architecture.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific (1S,3R) configuration enhances efficacy and selectivity.
• Fine Chemical Production: Serves as a versatile building block for creating complex fragrance molecules, flavors, and specialty polymers.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Material Science: Potential monomer or cross-linking agent for creating polymers with unique cyclopropane-based structural motifs.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 3-Ethenyl-2,2-Dimethyl-, Methyl Ester, (1S,3R)-
CAS No.	247129-72-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1S,3R)-3-Ethenyl-2,2-dimethylcyclopropanecarboxylic acid methyl ester; Methyl (1S,3R)-3-ethenyl-2,2-dimethylcyclopropanecarboxylate; (1S,3R)-3-Vinyl-2,2-dimethylcyclopropanecarboxylic acid methyl ester; Chiral vinylcyclopropane ester; (1S,3R)-VDMCC methyl ester; (1S,3R)-Methyl 3-vinyl-2,2-dimethylcyclopropanecarboxylate; (1S,3R)-3-Vinyl-2,2-dimethylcyclopropanecarboxylate methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized by advanced analytical techniques including chiral HPLC, GC, and NMR to guarantee high enantiomeric and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific customer requirements for R&D or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee (1S,3R)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.