Description

3-Azido-3-Deoxy-4-Hydroxy-Methyl-1,2-o-Isopropylidene-α-D-Ribofuranose is a high-purity, protected ribofuranose derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is valued for its unique azido functionality, which provides a versatile handle for further chemical transformations via click chemistry and other azide-specific reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and complex carbohydrate-based molecules.

Application

• Nucleoside & Nucleotide Analog Synthesis: A key chiral intermediate for constructing modified sugar moieties in potential antiviral and anticancer drug candidates.
• Carbohydrate Chemistry: Used in the stereoselective synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Click Chemistry Substrate: The azido group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer functionalization.
• Pharmaceutical Intermediate: Serves as a building block in the research and development of novel therapeutic agents targeting various diseases.
• Chemical Biology Probes: Facilitates the creation of labeled sugars and metabolic probes for studying biological pathways.
• Academic & Industrial R&D: Employed in methodological studies and process development for asymmetric synthesis.

Basic Information

Product Name	3-Azido-3-Deoxy-4-Hydroxy-Methyl-1,2-o-Isopropylidene-α-D-Ribofuranose
CAS No.	247025-10-1
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	1,2-O-Isopropylidene-3-azido-3-deoxy-4-C-hydroxymethyl-α-D-ribofuranose; 3-Azido-3-deoxy-4-C-(hydroxymethyl)-1,2-O-isopropylidene-α-D-ribofuranose; 3-Azido-1,2-O-isopropylidene-3-deoxy-4-C-(hydroxymethyl)-α-D-ribofuranose; 3-Azido-3-deoxy-4-hydroxymethyl-1,2-O-isopropylidene-α-D-ribofuranose; 3-Azido-4-hydroxymethyl-1,2-O-isopropylidene-α-D-ribofuranose; Protected 3-Azidoribofuranose; Azido Isopropylidene Ribose Derivative
EINECS	Contact for details

Quality Control

Our 3-Azido-3-Deoxy-4-Hydroxy-Methyl-1,2-o-Isopropylidene-α-D-Ribofuranose is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.