Description

1-Pyrrolidinecarboxylic Acid, 2-Fluoro-5-Oxo-, Ethyl Ester is a high-purity fluorinated pyrrolidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both a fluorinated moiety and a reactive keto-ester group, enabling precise modifications for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile precursor for constructing complex heterocyclic compounds and fluorinated analogs in academic and industrial R&D labs.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances requiring specific fluorinated structures.
• Material Science: Potential application as a monomer or modifier in the synthesis of specialized polymers with tailored properties.

Basic Information

Item	Detail
Product Name	1-Pyrrolidinecarboxylic Acid, 2-Fluoro-5-Oxo-, Ethyl Ester
CAS No.	246181-63-5
Molecular Formula	C8H12FNO3
Molecular Weight	189.18 g/mol
Synonyms	Ethyl 2-Fluoro-5-oxo-1-pyrrolidinecarboxylate; 2-Fluoro-5-oxopyrrolidine-1-carboxylic acid ethyl ester; 1-(Ethoxycarbonyl)-2-fluoro-5-pyrrolidinone; 2-Fluoro-5-oxo-1-pyrrolidinecarboxylic Acid Ethyl Ester; Ethyl 2-fluoro-5-oxopyrrolidine-1-carboxylate; 1-Carbethoxy-2-fluoro-5-pyrrolidinone; 246181-63-5; 2-Fluoro-5-oxo-pyrrolidine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 2-Fluoro-5-Oxo-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.