Description

1,2-Dichloro-3-Isocyanobenzene is a versatile aromatic isocyanate building block, essential for the synthesis of complex heterocyclic compounds and functional materials. Its core value lies in providing a reactive isocyanate group ortho to two chlorine substituents, enabling precise and controlled chemical transformations. This high-purity intermediate is critically needed by research institutions and manufacturers in the agrochemical and pharmaceutical industries for developing novel active ingredients and advanced polymers.

Application

• Agrochemical Intermediate: Key precursor for synthesizing novel herbicides, fungicides, and insecticides with specific activity profiles.
• Pharmaceutical Synthesis: Building block for the development of active pharmaceutical ingredients (APIs), particularly in creating urea and heterocyclic scaffolds.
• Polymer Chemistry: Used in the production of specialty polyurethanes and polyureas with enhanced chemical resistance or specific functional properties.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and functional coatings.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create complex aniline derivatives.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating custom chemical libraries in medicinal chemistry.

Basic Information

Product Name	1,2-Dichloro-3-Isocyanobenzene
CAS No.	245539-09-7
Molecular Formula	C7H3Cl2NO
Molecular Weight	188.01 g/mol
Synonyms	3-Isocyanato-1,2-dichlorobenzene; 1,2-Dichlorophenyl isocyanate; 2,3-Dichlorophenyl isocyanate; Isocyanic acid, 2,3-dichlorophenyl ester; 2,3-Dichloroisocyanatobenzene; 1,2-Dichloro-3-isocyanato-benzene; Benzene, 1,2-dichloro-3-isocyanato-
EINECS	Contact for details

Quality Control

Our 1,2-Dichloro-3-Isocyanobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.