Description

3,4-Pyridinedicarbonitrile, 2-Iodo-6-Methyl-5-Propyl- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of a pyridine core with reactive nitrile and iodo functional groups, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyridine-based structure.
• Ligand Synthesis: Acts as a starting material for creating complex chelating ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The iodo substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other complex structures.
• Nitrile Transformation Chemistry: The dicarbonitrile moiety provides handles for conversion into amides, acids, tetrazoles, and other heterocycles, expanding molecular diversity.

Basic Information

Product Name	3,4-Pyridinedicarbonitrile, 2-Iodo-6-Methyl-5-Propyl-
CAS No.	245079-24-7
Molecular Formula	C11H10IN3
Molecular Weight	311.12 g/mol
Synonyms	2-Iodo-6-methyl-5-propylpyridine-3,4-dicarbonitrile; 5-Propyl-2-iodo-6-methylpyridine-3,4-dicarbonitrile; 2-Iodo-5-propyl-6-methyl-3,4-pyridinedicarbonitrile; 3,4-Dicyano-2-iodo-6-methyl-5-propylpyridine; 245079-24-7; 2-Iodo-6-methyl-5-propyl-3,4-pyridinedicarbonitrile
EINECS	Contact for details

Quality Control

Our 3,4-Pyridinedicarbonitrile, 2-Iodo-6-Methyl-5-Propyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.