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Mpeg Bromoisobutyrate CAS NO 245070-97-7


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CAS No.:245070-97-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Mpeg Bromoisobutyrate is a specialized functionalized polyethylene glycol derivative, serving as a key macroinitiator in advanced polymerization techniques. Its primary value lies in enabling the precise synthesis of well-defined block copolymers and functional polymer architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, biomedical materials, and specialty polymer industries who require controlled polymer structures for applications like drug delivery systems and surface modification.

Application

  • Primary macroinitiator for Atom Transfer Radical Polymerization (ATRP) to create block copolymers.
  • Synthesis of PEG-based amphiphilic block copolymers for drug delivery nanocarriers (e.g., micelles, polymersomes).
  • Manufacturing of biocompatible polymer coatings for medical devices and implants to improve surface properties.
  • Production of functional hydrogels and smart materials with tailored degradation and release profiles.
  • Intermediate in the development of polymer-protein conjugates (PEGylation) to enhance therapeutic stability and efficacy.
  • Research and development of novel non-viral gene delivery vectors and diagnostic agents.

Basic Information

Product Name Mpeg Bromoisobutyrate
CAS No. 245070-97-7
Molecular Formula CnH2n+2Om (Variable, based on PEG chain length)
Molecular Weight Variable (Typically 350-5000 g/mol)
Synonyms Poly(ethylene glycol) methyl ether 2-bromoisobutyrate; mPEG-Br; α-Methoxy-ω-(2-bromoisobutyryloxy)poly(ethylene glycol); PEG Methyl Ether Bromoisobutyrate; Methoxy PEG Bromoisobutyrate; Bromoisobutyryl-terminated mPEG; ATRP Initiator mPEG-BIB; Poly(ethylene glycol) methyl ether bromoisobutyryl ester
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Quality Control

Our Mpeg Bromoisobutyrate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR for structural confirmation, GPC/SEC for molecular weight distribution (PDI), and titration for functional group quantification, ensuring consistency and reliability for sensitive polymerization reactions. Certificates of Analysis (COA) detailing purity, degree of functionalization, and residual solvent levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term stability, consider storing under an inert atmosphere (e.g., nitrogen or argon) and using desiccant in the storage area.

Specification

Item Specification
Appearance White to off-white waxy solid or viscous liquid
Identification (NMR) Conforms to structure
Assay (Functionalization) > 95%
Molecular Weight (Mn) As per customer grade (e.g., 350, 550, 2000, 5000)
Polydispersity Index (PDI) < 1.20 (by GPC)
Residual Solvent < 0.5% (by GC)
Water Content < 1.0% (by KF titration)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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