Description

1,4-Dioxaspiro[4.4]Non-6-Ene, 6-Ethynyl- (9Ci) is a high-value, functionalized spirocyclic building block featuring both an alkene and an alkyne group, making it a versatile intermediate for advanced organic synthesis. Its unique fused ring structure with orthogonal reactive handles is critical for constructing complex molecular architectures in pharmaceutical and materials research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and polymer science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for spirocyclic and constrained analogs.
• Agrochemical Synthesis: Used in research and development of new crop protection agents with complex ring systems.
• Material Science Research: Acts as a monomer or cross-linker in the development of specialty polymers and advanced organic frameworks.
• Chemical Biology Probes: Utilized in click chemistry applications via its alkyne moiety for bioconjugation and probe development.
• Catalyst Ligand Synthesis: Provides a scaffold for creating novel chiral or bidentate ligands for asymmetric catalysis.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Non-6-Ene, 6-Ethynyl- (9Ci)
CAS No.	244610-37-5
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	6-Ethynyl-1,4-dioxaspiro[4.4]non-6-ene; 6-Ethynyl-1,4-dioxaspiro[4.4]non-6-ene (9CI); 1,4-Dioxaspiro[4.4]non-6-ene, 6-ethynyl-; 244610-37-5; Spiro[1,3-dioxolane-2,1'-cyclopent[3]ene], 5'-ethynyl-3',4'-dihydro-; 5'-Ethynyl-3',4'-dihydrospiro[1,3-dioxolane-2,1'-cyclopent[3]ene]
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.4]Non-6-Ene, 6-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.