Description

(3As*,7As*)-Benzyl 2-(Bromomethyl)Hexahydrofuro[3,2-β]Pyridine -4(2H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with a reactive bromomethyl group. This compound is critical for synthetic chemists developing novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and metabolic disease research. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries seeking to build complex molecular architectures with high stereochemical control.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under GMP conditions.
• Asymmetric Synthesis: Exploited for constructing chiral centers in natural product analogs and specialty chemicals.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(3As*,7As*)-Benzyl 2-(Bromomethyl)Hexahydrofuro[3,2-β]Pyridine -4(2H)-Carboxylate
CAS No.	244056-98-2
Molecular Formula	C17H20BrNO3
Molecular Weight	366.25 g/mol
Synonyms	Benzyl 2-(bromomethyl)hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate; (3aR,7aR)-Benzyl 2-(bromomethyl)hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate; Hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylic acid, 2-(bromomethyl)-, phenylmethyl ester, (3aR,7aR)-rel-; Furo[3,2-b]pyridine intermediate; Bn-protected bromomethyl furopyridine carboxylate
EINECS	Contact for details

Quality Control

Every batch of (3As*,7As*)-Benzyl 2-(Bromomethyl)Hexahydrofuro[3,2-β]Pyridine -4(2H)-Carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Certificates of Analysis (COA) providing detailed results for identity, purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.