Description

N,n-Diethyl-cis-2,6-Dimethylpiperidium Hydroxide is a sterically hindered, strong organic base. This compound is valued for its high nucleophilicity and basicity in non-aqueous systems, making it a critical reagent for advanced organic synthesis and catalysis. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring a powerful, non-nucleophilic base under anhydrous conditions.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a key base for deprotonation and condensation reactions in the synthesis of complex active pharmaceutical ingredients (APIs).
• Catalyst and Ligand Precursor: Serves as a precursor for generating specialized catalysts and ligands used in asymmetric synthesis and polymerization processes.
• Agrochemical Manufacturing: Employed in the production of advanced herbicides and pesticides where specific stereochemistry is required.
• Polymer Chemistry: Used as an initiator or catalyst in the ring-opening polymerization of lactones and other monomers.
• Organic Synthesis Reagent: Facilitates a variety of reactions including alkylations, acylations, and eliminations under mild conditions.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Item	Details
Product Name	N,n-Diethyl-cis-2,6-Dimethylpiperidium Hydroxide
CAS No.	244048-96-2
Molecular Formula	C11H23NO
Molecular Weight	185.31 g/mol
Synonyms	N,N-Diethyl-cis-2,6-dimethylpiperidinium hydroxide; 1-Ethyl-2,6-dimethylpiperidine, N-ethyl derivative, hydroxide; cis-1,3-Diethyl-2,6-dimethylpiperidinium hydroxide; 2,6-Dimethyl-N,N-diethylpiperidinium hydroxide; DEDMPH; N,N-Diethyl-2,6-lupetidine hydroxide
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-cis-2,6-Dimethylpiperidium Hydroxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profile. We adhere to cGMP standards where applicable, and our quality management system is designed to meet the rigorous demands of our global clientele in research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.