Description

Carbamic Acid, (6S)-1,4-Dioxaspiro[2.3]Hex-6-Yl-, 1,1-Dimethylethyl Ester (9Ci) is a specialized chiral building block featuring a spirocyclic acetal-protected diol moiety. This compound is of significant value in pharmaceutical research and development, primarily serving as a key intermediate for the synthesis of complex, biologically active molecules. It is essential for medicinal chemists and process development scientists working in pharmaceutical and fine chemical industries who require high-purity, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic disorders.
• Asymmetric Synthesis: Used in the construction of complex molecular architectures requiring high enantiomeric purity, leveraging its (6S) stereocenter.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to introduce specific functional groups and stereochemistry.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of drug candidates under Good Manufacturing Practice (GMP) guidelines.
• Chemical Biology: Can be utilized as a molecular scaffold or probe in the study of biological pathways and target identification.
• Fine Chemical Production: Applied in the custom synthesis of high-value, low-volume specialty chemicals for advanced material science.

Basic Information

Product Name	Carbamic Acid, (6S)-1,4-Dioxaspiro[2.3]Hex-6-Yl-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	244023-85-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	(6S)-1,4-Dioxaspiro[2.3]hex-6-yl tert-butyl carbamate; tert-Butyl N-[(6S)-1,4-dioxaspiro[2.3]hex-6-yl]carbamate; (6S)-1,4-Dioxaspiro[2.3]hexane-6-carbamic acid 1,1-dimethylethyl ester; (S)-tert-Butyl (1,4-dioxaspiro[2.3]hexan-6-yl)carbamate; (S)-tert-Butyl 1,4-dioxaspiro[2.3]hexan-6-ylcarbamate; Boc-(S)-1,4-Dioxaspiro[2.3]hex-6-ylamine (protected form); (S)-6-(Boc-amino)-1,4-dioxaspiro[2.3]hexane
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (6S)-1,4-Dioxaspiro[2.3]Hex-6-Yl-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity (by HPLC), enantiomeric excess, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.