Description

1,2-o-Isopropylidene-β-L-Idofuranuronic Acid 5-o-Pivaloate 6,3-Lactone is a high-purity, protected sugar lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold for constructing complex molecules with precise stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other bioactive carbohydrate-based therapeutics.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Antiviral Drug Research: Used in the research and development of carbohydrate-based antiviral compounds targeting viral polymerases.
• Carbohydrate Chemistry: Serves as a protected idofuranuronic acid derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Chiral Pool Synthesis: Provides a source of defined L-idose configuration for the asymmetric synthesis of natural products and specialized fine chemicals.
• Chemical Biology Probes: Utilized in the creation of labeled or modified sugar molecules for investigating biological recognition and metabolic pathways.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring this specific stereochemical framework.

Basic Information

Product Name	1,2-o-Isopropylidene-β-L-Idofuranuronic Acid 5-o-Pivaloate 6,3-Lactone
CAS No.	243982-76-5
Molecular Formula	C14H20O7
Molecular Weight	300.30 g/mol
Synonyms	1,2-O-Isopropylidene-β-L-idofuranuronic acid 5-O-pivalate 6,3-lactone; (3aR,5R,6S,6aR)-5-[(2,2-Dimethylpropanoyl)oxy]-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-6-carboxylic acid, 6,3-lactone; 1,2-O-Isopropylidene-β-L-idofuranurono-6,3-lactone 5-O-pivalate; Pivaloyloxymethyl (POM) protected idose derivative; L-Idose derivative, 1,2:5,6-di-O-isopropylidene-α-L-idofuranurono-6,3-lactone pivalate; 5-O-Pivaloyl-1,2-O-isopropylidene-β-L-idofuranurono-6,3-lactone
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-β-L-Idofuranuronic Acid 5-o-Pivaloate 6,3-Lactone is manufactured under controlled conditions to ensure high chemical purity and lot-to-lot consistency, suitable for demanding research and process applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with internal quality standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.