Description

1-(3,4-Difluorobenzyl)-6-Oxo-n-Phenyl-1,6-Dihydro-3-Pyridinecarboxamide is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop next-generation drug candidates, leveraging its specific difluorobenzyl and pyridinecarboxamide motifs for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Kinase Inhibitor Precursor: Serves as a core scaffold in the development of potential kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke API development under cGMP conditions.
• Biochemical Tool Compound: May be utilized in vitro as a probe to study specific biological pathways and protein interactions.
• Fine Chemical Production: Integrated into multi-step synthetic routes for producing complex, high-value specialty chemicals.

Basic Information

Product Name	1-(3,4-Difluorobenzyl)-6-Oxo-n-Phenyl-1,6-Dihydro-3-Pyridinecarboxamide
CAS No.	242797-33-7
Molecular Formula	C19H14F2N2O2
Molecular Weight	340.33 g/mol
Synonyms	1-(3,4-Difluorobenzyl)-6-oxo-N-phenyl-1,6-dihydropyridine-3-carboxamide; 1,6-Dihydro-1-[(3,4-difluorophenyl)methyl]-6-oxo-N-phenyl-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 1-(3,4-difluorobenzyl)-1,6-dihydro-6-oxo-N-phenyl-; 242797-33-7; 1-(3,4-Difluorobenzyl)-6-oxo-N-phenyl-1,6-dihydropyridine-3-carboxamide; N-Phenyl-1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluorobenzyl)-6-Oxo-n-Phenyl-1,6-Dihydro-3-Pyridinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.