Description

2-[(4R)-4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-Pyridine is a high-purity, chiral oxazoline derivative that serves as a critical building block and ligand in advanced organic synthesis. Its value lies in its ability to impart stereoselectivity in catalytic reactions, enabling the production of enantiomerically pure compounds. This product is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those focused on asymmetric catalysis and the synthesis of active pharmaceutical ingredients (APIs).

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation and C-C bond-forming reactions.
• A key intermediate in the synthesis of complex, biologically active molecules for pharmaceutical research.
• Utilized in the development of novel catalysts for academic and industrial research programs.
• Employed in the preparation of enantiomerically pure compounds for material science applications.
• Used as a reference standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2-[(4R)-4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-Pyridine
CAS No.	242482-28-6
Molecular Formula	C14H20N2O
Molecular Weight	232.33 g/mol
Synonyms	(4R)-4-(tert-Butyl)-4,5-dihydro-2-(pyridin-2-yl)oxazole; (R)-4-(tert-Butyl)-2-(2-pyridyl)-4,5-dihydrooxazole; (R)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)pyridine; (R)-tert-Butyl Oxazoline Pyridine Ligand; Pyridine, 2-[(4R)-4-(1,1-dimethylethyl)-4,5-dihydro-2-oxazolyl]-; (R)-t-BuPyOx; (R)-2-(2-Pyridyl)-4-tert-butyl-2-oxazoline
EINECS	Contact for details

Quality Control

Our 2-[(4R)-4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.