Description

Cyclopropanecarboxylic Acid, 2,2-Dimethyl-3-(1E)-1-Propenyl-, (1R,3R)-Rel- (9Ci) CAS NO 240494-66-0 is a high-purity, stereochemically defined cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique, strained three-membered ring structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting specific biological pathways.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the defined spatial configuration is crucial for bioactivity.
• Advanced Material Research: Serves as a precursor for specialty polymers and liquid crystals where the rigid cyclopropane ring can impart desired thermal and mechanical properties.
• Asymmetric Catalysis Ligand Precursor: Employed in the development of novel chiral ligands and catalysts for enantioselective synthesis.
• Flavor & Fragrance Ingredient Synthesis: Used in the production of high-value, complex aroma chemicals requiring specific stereochemistry.
• Academic & Contract Research: A valuable tool for synthetic organic chemists in universities and CROs exploring new chemical methodologies and reaction pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2,2-Dimethyl-3-(1E)-1-Propenyl-, (1R,3R)-Rel- (9Ci)
CAS No.	240494-66-0
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(1R,3R)-rel-2,2-Dimethyl-3-[(1E)-1-propen-1-yl]cyclopropanecarboxylic Acid; Chrysanthemic Acid Isomer; (1R,3R)-trans-Chrysanthemic Acid (rel); 2,2-Dimethyl-3-(trans-1-propenyl)cyclopropanecarboxylic Acid (rel); (1R,3R)-rel-2,2-Dimethyl-3-(1-propenyl)cyclopropanecarboxylic Acid; (1R,3R)-rel-Chrysanthemumic Acid; (1R,3R)-rel-2,2-Dimethyl-3-(trans-propen-1-yl)cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2,2-Dimethyl-3-(1E)-1-Propenyl-, (1R,3R)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, chiral purity (enantiomeric excess), and chemical assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources, strong oxidizing agents, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.