Description

2-Oxa-7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical manufacturers and R&D organizations specializing in novel drug discovery, especially for central nervous system (CNS) and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical entities in drug discovery and lead optimization programs.
• Protease Inhibitor Development: The spirocyclic structure is valuable in the design and synthesis of protease inhibitors for therapeutic applications.
• CNS Drug Candidates: Serves as a building block for developing potential treatments targeting neurological disorders.
• Antiviral Agent Synthesis: Employed in the research and development of novel antiviral compounds.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	2-Oxa-7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	240401-27-8
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	tert-Butyl 2-oxa-7-azaspiro[3.5]nonane-7-carboxylate; 7-Boc-2-oxa-7-azaspiro[3.5]nonane; 2-Oxa-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-2-oxa-7-azaspiro[3.5]nonane; Boc-2-oxa-7-azaspiro[3.5]nonane; 240401-27-8; 1,1-Dimethylethyl 2-oxa-7-azaspiro[3.5]nonane-7-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Oxa-7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and all relevant specifications are provided with each shipment. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.